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Molecular Biology and Biotechnology

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This cluster focuses on two main themes: 

 

Bio-molecular structure and function 

 

Mission Statement

The structure of biological molecules underpins their function.  All pharmaceutical drugslysozyme crystals and agricultural pest and herbicides, whether designed from structural information or discovered by mining for active molecules derive their efficacy and specificity from their unique structure.

The group applies its expertise in the areas of recombinant DNA technology, protein production and purification, X-ray crystallography and computational modelling to determine the structure and function of biologically significant molecules.  In doing so it provides a basis on which new and improved pharma- and agri-ceutical's can be manufactured.

 

The aims of the Flinders Bio-molecular structure and function group are to:

  • Identify specific bio-molecular targets for structural determinations;

  • Relate structure to function using transgenic approaches;

  • Increase the understanding that links structure to structure prediction by computational modelling software;

  • Develop further links with biotechnology industries (local and abroad) for manufacture and down-stream processing of related drugs, and products designed from our research.

Molecular and Microbial Biotechnology 

 

Mission Statement
All life processes ultimately depend on sequence information contained in DNA that can be both observed as a means of identifying individuals and manipulated to alter and improve specific gene functions and practical applications of biological systems. We capitalise on the expertise and intellectual property established by cluster members in the manipulation and characterisation of DNA to extend knowledge, collaborations and commercial development of IP and grant income.

 

The aims of the Flinders Molecular and microbial biotechnology group are to:

  • Generate additional tools for profiling DNA for forensic, wildlife  enforcement and scientific applications;

  • Develop tools to study and improve applications of complex  microbial systems;

  • Develop further start-up biotechnology enterprise based on Flinders IP;

  • Establish additional links with biotechnology industries (local and abroad).


Academic Staff and Research Foci

Current academic members of the cluster include: 

 

Dr Melissa Brown (cluster leader)

  • Multidrug resistance in bacteria

Dr Cathy Abbott

  • Dipeptidyl peptidases in human disease

Dr Peter Anderson

  • Structural studies of plant disease resistance proteins

Prof Andy Ball

  • Bioremediation of contaminated land and water

  • Bio-utilization of waste organic streams

Emeritus Prof Leigh Burgoyne

  • DNA storage and retrieval technologies

  • Forensic profiling tools for illicit drugs and trace soil

Prof David Catcheside

  • Molecular mechanism of recombination, directed evolution of genes and proteins

  • Forensic profiling tools for illicit drugs and trace soil

Prof Amanda Goodman

  • DNA fingerprinting of Australian reptiles

  • Regulation of chitinase production in marine bacteria

  • Recycling in the marine environment by biofilm-forming bacteria

Dr Ian Menz

  • Crystal structures of malarial proteins as a basis for rational drug design

Dr Kathy Schuller

  • Oxidative stress and antioxidants in fish, malaria parasite and plants

Dr Kathy Soole

  • Mitochondrial enzymes as target sites for; antimicrobials and development of stress-resistant plants

  • Organic acid metabolism in plants and its applications in wine production and bioremediation

Dr James Stangoulis

  • Molecular & physiological mechanisms of trace element transport in plants

 

Flinders Bioremediation

 

 

 

 

Click on logo for information on Flinders Bioremediation.


 


Programs

Connections with government, Industry and Community Groups

Current Research Higher Degree Students

Current Honours Students 

  • Sam Aleer
  • Joanna Cyza
  • Abbe Harris
  • Mel Haynes
  • Amy Koschella
  • Bernard Lee
  • Kym McNicholas
  • Valene See

Placements & Employment of Honours and Higher Degree Research GraduatesI have saved a MolecularCluster_Placement.doc on the shared drive until I get this info from cluster, kb 24/5/0

Student Club

Flinders University Biotechnology Association (FUBA)

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